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Autonomic & Vascular Function Assessments


Primary Care, Cardiology, Pulmonology, Endocrinology, Neurology, Pain Management


TopDocDX Combo Pro technology is a scientific breakthrough in health management and diagnostic.
TopDocDX Combo Pro allows medical professionals, to see more and know more than ever before.

TopDocDX Combo Pro combines ANS, SudoCheck, ABI and PAD technologies in a clinically powerful and easy to use non-invasive system.

TopDocDX Combo Pro is a valuable ANS and Sudomotor testing tool in diagnosing hidden illnesses. Having the ability to quickly and easily test patients and receive immediate comprehensive interpretive reports after the test is invaluable to medical practitioners.



TopDocDX ANS System provides comprehensive, fully automated Autonomic Function Testing (ANS) equipment that is useful for physicians to gauge their patient's health and uncover hidden disease.



TopDocDX Vascular+ is an innovative cuff-based system for performing the Pulse Wave Velocity Analysis (PWV), Ankle-Brachial index (ABI) and TBI exam to assist in the diagnosis of Peripheral Arterial disease (PAD), Arterial Stiffness and Endothelial Dysfunction.



SudoCheck system helps clinicians with Peripheral Neuropathies and Sudomotor function evaluation. SudoCheck assessment focus on small nerve fibers within the autonomic nervous system, and their ability to quickly regenerate.

How It Helps Your Patients:

  • Evaluation of current health situation - symptoms, medications and therapy reactions;

  • Assessment of possible adequacy of the recovery process;

  • Initiation of Physician's focus to treat the onset of chronic situations or severity of the diseases;

  • Evaluation of the prognosis and treatment outcomes;

  • Identification of abnormalities in cardiovascular, cerebrovascular system and overall health assessment;

  • Blood circulatory status - age of blood vessels based on arterial elasticity, peripheral circulatory status, organic/functional abnormality of the blood vessels;

  • Prediction and progression of Arteriosclerosis, Obesity, Hypertension, Hyperlipidemia and Diabetes;

  • Useful as a health barometer;

How It Helps You:

  • Monitoring current health of the individual patient closely;

  • Verifying the efficacy of current treatment protocol and intervention;

  • Examining patients for Cardiac Autonomic Neuropathy (CAN) and Diabetes Autonomic Neuropathy (DAN);

  • Measuring the Metabolic Syndrome, Hypertension, Heart Failure;

  • Predicting burn-out syndrome, anxiety, depression, psychological conditions;

  • Exploring Asthma, COPD, Palpitations, Pain management, Sleep apnea;

  • Optimization of treatment for each individual patient;

  • Immediate reports - qualitative, quantitative and graphic analysis and results of ANS balance, cardiovascular, stress, fitness and overall health assessment, with ability for comparison with patient case history and necessary procedural actions;

  • Efficient patient-centered multiple symptoms treatment management;

Physician Benefits

TopDocDX Combo Pro is a valuable tool in diagnosing hidden illnesses. Having the ability to quickly and easily test patients, and receive immediate comprehensive interpretive reports after the test is invaluable to medical practitioners.
Testing takes only 15 minutes to run. Full battery of tests interpretive reports are generated immediately after testing. The reports are very easy to read and understand by the physician.TopDocDX Combo Pro has 39 standardized tests. In addition, provides with the ability to customize testing protocols and create custom templates.

Why Test ANS?

  • "According to Published Studies "Cardiovascular autonomic neuropathy occurs in about 17% of patients with type 1 diabetes and 22% of those with type 2"

  • "Of patients with symptomatic autonomic dysfunction, 25% to 50% die within 1 to 5 years of diagnosis."

  • "A patient's history and physical examination are ineffective for early detection of CAN, and therefore noninvasive tests that have demonstrated efficacy are required".

  • "Screening for Autonomic Neuropathy should be instituted at Diagnosis of Type 2 Diabetes and 5 years after the diagnosis of type 1 Diabetes - 2005 ADA Standard of Diabetes Care"

  • "Although it can cause severe cardiovascular problems and sudden death, surveys show that only 2% of people with diabetes are tested for cardiovascular autonomic neuropathy (CAN)".

The TopDocDX Combo Pro system is a Class II medical device that is US FDA 510(K) cleared.

TopDocDX Combo Pro testing procedure is covered by the most major insurance providers.


Non-Invasive, Painless, Preventative Testing,  to

Prevent Possible Life Threatening Conditions From Before They Are A Threat

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